Heteronuclear single quantum coherence spectroscopy

Heteronuclear single quantum coherence (HSQC) spectroscopy is a two-dimensional NMR (nuclear magnetic resonance) technique primarily used for the analysis of complex organic molecules, particularly those containing multiple types of nuclei, such as carbon-13 (\(^{13}C\)) and proton (\(^1H\)). The HSQC method allows for the correlation of these different nuclei, enabling chemists to better understand molecular structures and interactions.