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Zinc finger nucleases (ZFNs) are a type of engineered DNA-binding protein that facilitate targeted editing of genomic DNA. They are composed of two main components: a DNA-binding domain formed by zinc finger motifs, and a nuclease domain, typically derived from the FokI restriction enzyme. ### Components of ZFNs: 1. **Zinc Finger Motifs**: These are small protein domains that can bind to specific DNA sequences.

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