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Nonribosomal peptides are a class of peptides that are synthesized in cells by nonribosomal peptide synthetases (NRPSs), which are large multi-modular enzyme complexes. Unlike ribosomal peptides, which are produced through the classical ribosomal translation of messenger RNA, nonribosomal peptides are synthesized from amino acids in a sequence that is determined by the NRPSs, not by mRNA templates. This allows for a greater diversity of structures and modifications.

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