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As of my last knowledge update in October 2023, here are some of the teams that have historically had the highest winning percentages in NCAA Division I men's college basketball: 1. **Kentucky Wildcats** 2. **North Carolina Tar Heels** 3. **Duke Blue Devils** 4. **Kansas Jayhawks** 5. **UCLA Bruins** These programs have consistently been among the top in terms of overall winning percentage due to their successful seasons, tournament appearances, and championships.

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