Conformational entropy

Conformational entropy is a concept from thermodynamics and statistical mechanics that refers to the number of different ways a molecule can arrange itself in space while maintaining its overall structure. It is a key component of the free energy of a system and plays a significant role in determining the stability and reactivity of molecular systems. In more technical terms, conformational entropy quantifies the diversity of conformations (the various spatial arrangements of atoms in a molecule) available to a given molecular system.