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Amphipathic lipid packing sensor motifs (ALPS motifs) are structural features found in certain proteins that can interact with lipid membranes in specific ways. These motifs typically contain both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions, allowing them to interact with the amphipathic nature of lipid bilayers. **Key Characteristics of ALPS Motifs:** 1.

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