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Technetium-99m (99mTc) sestamibi is a radioactive tracer used in nuclear medicine, particularly in the field of imaging and diagnostics. It is a complex of the radioisotope technetium-99m with the compound sestamibi (mibi stands for methoxyisobutylisonitrile), which is a lipophilic cation that preferentially accumulates in viable myocardial tissue due to its affinity for cells with high mitochondrial activity.

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