Salt bridge (protein and supramolecular)

A salt bridge refers to a non-covalent interaction that occurs between oppositely charged ionizable groups, typically amino acid side chains, in a protein or in supramolecular assemblies. Here’s a breakdown of salt bridges in both contexts: ### In Proteins: 1. **Definition**: A salt bridge in proteins usually involves the electrostatic attraction between the carboxylate group (e.g., from aspartate or glutamate) and an ammonium group (e.g.