Matrix-assisted laser desorption electrospray ionization

Matrix-assisted laser desorption electrospray ionization (MALDI-ESI) is a mass spectrometry technique that combines two powerful ionization methods: matrix-assisted laser desorption/ionization (MALDI) and electrospray ionization (ESI). This hybrid technique is utilized to analyze a wide range of biomolecules, including proteins, peptides, and other large biomolecular complexes.