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ArcLight is a genetically encoded fluorescent protein used in neuroscience and cellular biology to study neuronal activity. Developed as a tool for imaging and measuring membrane potential changes in live cells, ArcLight is engineered to provide a response to voltage changes across the cell membrane. When the membrane potential changes due to neuronal activity, ArcLight exhibits a corresponding change in its fluorescence properties. This allows researchers to visualize the electrical activity of neurons in real-time using fluorescence microscopy techniques.

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